The £30m, 81,000 sq ft scheme is set to open in 2022 after securing unanimous backing from Bolton Council.
The facility is a joint venture between the University of Bolton, Bolton NHS Foundation Trust, Bolton Council, and Bolton College. It is expected to support around 3,000 students a year, with 1,000 apprentices in health and social care roles.
Greater Manchester Combined Authority has granted £10m to the development through its Skills Capital Fund.
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